Nuno Espirito Santo faces a tough test in his second game as West Ham manager, as his team travels to face Arsenal, who have shown their strength in their recent win at Newcastle.
West Ham, however, has a favorable record at the Emirates Stadium, having won their last two matches against Arsenal on their home turf.
This achievement is all the more impressive considering Arsenal's strong home record, having lost only four of their last 42 Premier League matches at the Emirates Stadium.
The last 10 points earned by West Ham have come from away games, with the team looking to continue their winning streak on the road.
Jarrod Bowen will be a key player for West Ham, having scored against Arsenal last season and having 11 goal involvements in his last 12 Premier League appearances.
Bukayo Saka will also be looking to make his 200th appearance for Arsenal, but the team's history in London derbies suggests that West Ham may face an uphill battle.
Arsenal have lost more Premier League London derbies than any other team and have only lost one of their last eight English top-flight games, drawing one and winning the other six.
The Gunners have also become proficient at scoring from set pieces, with nine of their last 14 Premier League goals coming from corners and free kicks.
Gabriel has been a key player in this area, with 18 Premier League goals for Arsenal, including his 18th goal from a corner.
Bukayo Saka will also be looking to reach 100 Premier League goal involvements, and with West Ham's porous defense, a goal or assist may be within reach.
Both teams will be missing key players due to injuries and suspensions, with West Ham's Tomas Soucek serving a three-match ban and Gabriel facing a late fitness test.
The match is crucial for both teams, with Arsenal looking to put pressure on Liverpool, who face Chelsea directly after the London derby, and West Ham seeking to gain more time to work with their squad before their next assignment against Brentford.